#THE GOOD THE BAD AND THE UGLY IMAGES PROFESSIONAL#
#THE GOOD THE BAD AND THE UGLY IMAGES SERIES#

Whether you like it or not, people form opinions on your appearance. Being a Recruiter, I spend every day on LinkedIn and introduce myself to new people, over LinkedIn, all the time. It took a while but I feel I now have a picture that, well, looks like me! And the me I want everyone else to see online. I trimmed the beard, had a haircut, ironed a shirt and stood in front of a brick wall. About 9 months ago I asked my girlfriend, with the help of her DSLR camera, to help get me a new profile pic. So you may not have the same pic for Facebook, Twitter or Tinder.

#THE GOOD THE BAD AND THE UGLY IMAGES PROFESSIONAL#

On LinkedIn, you want the вЂat workвЂ™ version of yourself to shine through because LinkedIn is a professional networking site.

we dress and act differently when jogging, meeting friends, at work etc. In the video, it quite rightly mentions that we all have different versions of ourselves i.e. (Jordan St Charles, Ph.D., is an Intramural Research and Training Award fellow in the DNA Replication Fidelity Group at NIEHS.LinkedIn has a great 53 second video to help users snap the right photo for your profile. But then the window would close, and the transporter would be there to protect the brain against other nasty things,вЂќ he said, demonstrating the complexity of the challenges researchers face. вЂњSo by manipulating the dose and timing of the drug, I could create a time window when Taxol would go in, since the transporter is not working. Patients would be treated with both a drug that signals the transporter to be turned off and a therapeutic drug, such as Taxol. To avoid these side effects, MillerвЂ™s lab focuses on finding ways past the transporters by using cell-signaling molecules that would turn off the transporter. Unfortunately, this method was only effective with levels of cyclosporine high enough to cause side effects. In one experiment, the transporter was blocked with a drug called cyclosporine, which allowed chemotherapeutics to get across the barrier. He showed several experiments featuring his favorite transporter, p-glycoprotein. Research in MillerвЂ™s lab focuses on finding ways to move drugs that have been shown to be effective in the test tube past the blood-brain barrier, so they can be effective in treating tumors in the brain. Miller explained that in addition to keeping out dangerous chemicals, the blood-brain barrier may also keep out helpful drugs, such as chemotherapeutics. Efflux transporters recognize and block foreign chemicals. There are plugs, called tight junctions, between the endothelial cells and transporters on the cell membranes. Blood entering the brain moves into small capillaries lined with endothelial cells, which Miller compared to a brick wall. The brain is protected by a feature known as the blood-brain barrier. The blood-brain barrier and research in the Intracellular Regulation GroupД¬ertain tissues, such as the brain, placenta, and testes, have additional barriers to drugs. вЂњFrom the liver, many of these metabolites get dumped into the blood and distributed throughout the body,вЂќ said Miller. Ingested drugs enter the circulatory system through the small intestine, then travel to the liver, where they can be metabolized into different forms. He explained that drugs move through the body using the circulatory system.

Miller began his talk by defining pharmacology, the science of how drugs interact with the body. вЂњFeedback from participants has been positive, with people consistently commenting that the talks increase their knowledge of the topic, and that they enjoy learning more about research conducted at the institute,вЂќ said Boyles. Previous talks were given by John Schelp, Geoffrey Mueller, Ph.D., and Richard Kwok, Ph.D., with topics ranging from allergies to epidemiology.

#THE GOOD THE BAD AND THE UGLY IMAGES SERIES#

9, David Miller, Ph.D., deputy chief of the Signal Transduction Laboratory, described how therapeutic drugs and other foreign chemicals move around the body.Д«ig Picture, Small Talk is a new series organized by Abee Boyles, Ph.D., of the National Toxicology Program, and by a cross-divisional organizing committee with the goal of presenting NIEHS research in a format that is more accessible to nonspecialists. In his Big Picture, Small Talk seminar Dec. A place for peminat-peminat of The Good, the Bad and the Ugly to view, download, share, and discuss their kegemaran images, icons, foto-foto and wallpapers. Geoff Mueller, Ph.D., left, and Lars Pedersen, Ph.D., both of the Genome Integrity and Structural Biology Laboratory, pondered the difficulties of the blood-brain barrier.

The good the bad and the ugly images